THE ANTIBACTERIAL EFFECTS OF ESSENTIAL OIL FROM GALANGAL RHIZOME ALPINIA GALANGA (LINN.) PIERREON RAT (RATTUS NORVEGICUS L.) WERE INFECTED BY SALMONELLA TYPHI

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UEU » Journal » Farmasi
Posted by [email protected] at 15/01/2020 12:27:07 • 731 Views

THE ANTIBACTERIAL EFFECTS OF ESSENTIAL OIL FROM GALANGAL RHIZOME ALPINIA GALANGA (LINN.) PIERREON RAT (RATTUS NORVEGICUS L.) WERE INFECTED BY SALMONELLA TYPHI

Created by :
Dr. APRILITA RINA YANTI EFF, M.Biomed, Apt ( 215020572 )
Dr. SRI TEGUH RAHAYU, S.Farm, M.Farm, Apt

Subject:	ANTIBAKTERI MINYAK ESENSIAL
Alt. Subject :	ANTIBACTERIAL ESSENTIAL OIL
Keyword:	ANTIBACTERIAL EFFECTS SALMONELLA TYPHI

Description:

Objectives: The research was aimed to assess the effect of essential oil of Galangal rhizome (Alpinia galanga (Linn.) Pierre.) in vivo by Widal test using mice infected with Salmonella typhi. Methods: Antibacterial activity of the essential oils was determined by Widal test for measuring antibody titre of Salmonella antigen. Study was begun by isolating the essential oils galangal rhizome (Alpinia galanga (Linn.) Pierre.) followed by tested the antibacterial activity of Salmonella typhi in rats (Rattus norvegicus L.). Mice were divided into six treatment groups, ie normal control group, negative control group given Gum Arabic 10%, positive control group given the suspension of chloramphenicol 8 mg/250 g BW, experimental group 1 given the emulsion of essential oil at the dose 25 mg / ml, experimental group given the emulsion of essential oil at the dose 50 mg / ml, and the experimental group 3 given the emulsion of essential oil at the dose 75 mg / ml. Before treated, mice were adapted for 2 weeks and measurement of antibody titer (Widal test 1) as a baseline, then the mice induced by Salmonella typhi suspension oral. On day 8 titre antibody was measuring (Widal test 2) and followed the administration of the test material orally 3 times a day for 7 consecutive days - respectively. On day 14 measurements of antibody titer was repeated (Widal test 3) to see the effectiveness of treatment. Results: An essential oil from Galangal (Alpinia galanga (Linn.) Pierre.) at the dose 25mg/ml, 50 mg/ml and 75 mg/ml can reduce antibody titer of Salmonella antigen. Conclusion: The results obtained in the study show that essential oils from galangal rhizome possess antibacterial effect against Salmonella typhi

Date Create	:	15/01/2020
Type	:	Text
Format	:	PDF
Language	:	Indonesian
Identifier	:	UEU-Journal-11_0070
Collection ID	:	11_0070

Source :
Asian Journal of Pharmaceutical and Clinical Research, Vol. 9, Suppl. 1, 2016

Relation Collection:
Fakultas Ilmu Kesehatan

Coverage :
Civitas Akademika Universitas Esa Unggul

Rights :
@2020 Perpustakaan Universitas Esa Unggul

Publication URL :
https://digilib.esaunggul.ac.id/the-antibacterial-effects-of-essential-oil-from-galangal-rhizome-alpinia-galanga-linn-pierreon-rat-rattus-norvegicus-l-were-infected-by-salmonella-typhi-14154.html

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